Home/IP3
Molecule
3 pathways

IP3

Found in 3 curated pathways across 2 categories.

Interaction Network

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Active In Categories

signalingimmune

Frequently Co-occurring Molecules

DAG×2Ca²⁺×2GPCRs×1Gαs/Gαi/Gαq/Gα12×1Gβγ×1cAMP×1β-Arrestin×1GRKs×1Calmodulin×1cADPR×1NAADP×1STIM1×1

Frequently Co-occurring Enzymes

Adenylyl cyclase×1PLCβ×1PKA×1PKC×1GRK kinases×1Phosphodiesterases (PDEs)×1SERCA (Ca²⁺-ATPase)×1IP3 receptor×1Ryanodine receptor×1CaMKII×1Calcineurin×1PMCA×1

Cross-Referenced Pathways

3 direct · 6 cross-referenced · 9 shown

Cross-Referenced

6
— connected via related pathways
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Signal Transduction

MAPK/ERK Pathway

RAS–RAF–MEK–ERK cascade transducing growth factor signals to the nucleus.

Growth factors (EGF, PDGF)RAS-GTPRAF+3
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Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6
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Signal Transduction

NF-κB Pathway

Master regulator of inflammation, immunity, and cell survival.

NF-κB (p65/RelA, p50)IκBαIKKα/β/γ+4
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Immune Response

T Cell Receptor Signaling

Antigen-specific activation of T lymphocytes via TCR-MHC interaction.

TCR-CD3 complexMHC-peptideCD4/CD8+7
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Membrane Transport

Ion Channel Signaling

Selective ion flux through membrane channels driving electrical and chemical signals.

Na⁺K⁺Ca²⁺+5
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Neuronal

Synaptic Transmission

Chemical neurotransmission across synaptic clefts between neurons.

GlutamateGABAAcetylcholine+6