Home/β-Arrestin

Molecule

1 pathway

β-Arrestin

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

GPCRs×1 Gαs/Gαi/Gαq/Gα12×1 Gβγ×1 cAMP×1 IP3×1 DAG×1 Ca²⁺×1 GRKs×1

Frequently Co-occurring Enzymes

Adenylyl cyclase×1 PLCβ×1 PKA×1 PKC×1 GRK kinases×1 Phosphodiesterases (PDEs)×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Signal Transduction

G Protein-Coupled Receptor (GPCR) Signaling

Seven-transmembrane receptors activating heterotrimeric G proteins.

GPCRsGαs/Gαi/Gαq/Gα12Gβγ+6

Cross-Referenced

3

— connected via related pathways

Signal Transduction

MAPK/ERK Pathway

RAS–RAF–MEK–ERK cascade transducing growth factor signals to the nucleus.

Growth factors (EGF, PDGF)RAS-GTPRAF+3

Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6

Signal Transduction

Calcium Signaling

Ca²⁺ as a universal second messenger controlling diverse cellular processes.

Ca²⁺CalmodulinIP3+4