// Curriculum

12 modules · Core track

Each module includes a track-aware summary, evidence-graded claims, a quiz, flashcards, and pointers into the Pathway Atlas. Switch tracks in the sidebar.

01

Why Pathways Matter

30 min

Why every clinician and researcher should think in pathways, not isolated molecules.

CoreClinicalResearchTier 1 · 2 · 3 · 4 · 5
02

Reading Pathway Diagrams

35 min

Arrows, T-bars, dashed lines — what they mean and where they lie.

CoreClinicalResearchTier 1 · 2
03

Glycolysis & the TCA Cycle

70 min

The two engines of central carbon metabolism — and why both matter at the bedside.

CoreClinicalResearchTier 1 · 2
04

Oxidative Phosphorylation

60 min

Electron transport chain, proton-motive force, and the small drugs that uncouple them.

CoreClinicalResearchTier 1
05

Lipid & Amino Acid Metabolism

65 min

Beta-oxidation, ketogenesis, urea cycle, and the bedside-relevant inborn errors.

CoreClinicalResearchTier 1 · 2
06

Signal Transduction Basics

55 min

GPCRs, second messengers, and the universal grammar of cell signaling.

CoreClinicalResearchTier 1 · 2
07

RTKs, RAS-MAPK & PI3K-AKT

70 min

The two cascades that drive most solid tumors — and their targeted therapies.

CoreClinicalResearchTier 1 · 2
08

Wnt, Hedgehog & Notch

55 min

Three developmental pathways that re-emerge as drivers of cancer and stem-cell biology.

CoreClinicalResearchTier 1 · 2
09

Immune Signaling Pathways

65 min

TLRs, JAK-STAT, and NF-κB — the wiring behind biologics and autoimmune disease.

CoreClinicalResearchTier 1 · 2 · 3
10

Apoptosis & Cell Cycle Control

60 min

How cells decide to divide — or die — and the drugs that exploit those decisions.

CoreClinicalResearchTier 1 · 2
11

Disease Pathways & Drug Targets

75 min

From pathway knowledge to prescribing decisions and trial design.

CoreClinicalResearchTier 1 · 2 · 3
12

Capstone: Cross-Pathway Reasoning

90 min

Integrate metabolism, signaling, and cell-fate decisions in a series of clinical and research vignettes.

CoreClinicalResearchTier 1 · 2 · 3