Home/Citrate synthase

Enzyme

2 pathways

Citrate synthase

Found in 2 curated pathways across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

Acetyl-CoA×2 Isocitrate×2 Succinate×2 Malate×2 Oxaloacetate×2 Citrate×1 α-Ketoglutarate×1 Succinyl-CoA×1 Fumarate×1 Glyoxylate×1

Frequently Co-occurring Enzymes

Malate dehydrogenase×2 Isocitrate dehydrogenase×1 α-Ketoglutarate dehydrogenase×1 Succinate dehydrogenase×1 Isocitrate lyase×1 Malate synthase×1 Aconitase×1

Cross-Referenced Pathways

2 direct · 4 cross-referenced · 6 shown

Direct Involvement

2

Citric Acid Cycle (Krebs Cycle)

Oxidizes acetyl-CoA to CO₂, generating GTP, NADH, and FADH₂.

Acetyl-CoACitrateIsocitrate+6

Glyoxylate Cycle

Net conversion of acetyl-CoA to oxaloacetate, bypassing CO₂ loss steps of TCA.

Acetyl-CoAIsocitrateGlyoxylate+3

Cross-Referenced

4

— connected via related pathways

Glycolysis

The breakdown of glucose into pyruvate, yielding ATP and NADH.

GlucoseGlucose-6-phosphateFructose-1,6-bisphosphate+4

Oxidative Phosphorylation

Electron transport chain coupled to ATP synthesis via chemiosmosis.

NADHFADH₂O₂+4

β-Oxidation of Fatty Acids

Sequential removal of 2-carbon units from fatty acids as acetyl-CoA.

Fatty acyl-CoAAcetyl-CoACarnitine+5

Gluconeogenesis

Synthesis of glucose from non-carbohydrate precursors.

PyruvateOxaloacetatePhosphoenolpyruvate+4