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Metabolic Pathways

Energy production, biosynthesis, and catabolism

Metabolic

Glycolysis

The breakdown of glucose into pyruvate, yielding ATP and NADH.

GlucoseGlucose-6-phosphateFructose-1,6-bisphosphate+4
Metabolic

Citric Acid Cycle (Krebs Cycle)

Oxidizes acetyl-CoA to CO₂, generating GTP, NADH, and FADH₂.

Acetyl-CoACitrateIsocitrate+6
Metabolic

Oxidative Phosphorylation

Electron transport chain coupled to ATP synthesis via chemiosmosis.

NADHFADH₂O₂+4
Metabolic

Pentose Phosphate Pathway

Generates NADPH and ribose-5-phosphate for biosynthesis.

Glucose-6-phosphate6-PhosphogluconateRibulose-5-phosphate+3
Metabolic

β-Oxidation of Fatty Acids

Sequential removal of 2-carbon units from fatty acids as acetyl-CoA.

Fatty acyl-CoAAcetyl-CoACarnitine+5
Metabolic

Photosynthesis – Light Reactions

Capture of light energy to produce ATP and NADPH, with O₂ as a byproduct.

Chlorophyll a/bH₂OO₂+5
Metabolic

Calvin Cycle (Light-Independent Reactions)

Fixes CO₂ into organic molecules using ATP and NADPH from light reactions.

CO₂Ribulose-1,5-bisphosphate (RuBP)3-Phosphoglycerate (3-PGA)+3
Metabolic

Gluconeogenesis

Synthesis of glucose from non-carbohydrate precursors.

PyruvateOxaloacetatePhosphoenolpyruvate+4
Metabolic

Glycogen Metabolism

Synthesis and degradation of glycogen for glucose storage and release.

GlycogenUDP-glucoseGlucose-1-phosphate+5
Metabolic

Urea Cycle

Converts toxic ammonia to urea for excretion.

NH₃ (ammonia)CO₂Carbamoyl phosphate+6
Metabolic

Amino Acid Catabolism

Degradation of amino acids to metabolic intermediates and ammonia.

Amino acidsα-KetoglutarateGlutamate+4
Metabolic

Nucleotide Biosynthesis

De novo and salvage pathways for purine and pyrimidine nucleotide production.

PRPPIMPAMP+6
Metabolic

Folate / One-Carbon Metabolism

Transfer of one-carbon units for nucleotide synthesis, methylation, and amino acid metabolism.

Tetrahydrofolate (THF)5-Methyl-THF5,10-Methylene-THF+6
Metabolic

Heme Biosynthesis

Eight-step pathway producing heme from glycine and succinyl-CoA.

GlycineSuccinyl-CoAδ-Aminolevulinic acid (ALA)+5
Metabolic

Ketogenesis

Hepatic production of ketone bodies from excess acetyl-CoA during fasting.

Acetyl-CoAAcetoacetyl-CoAHMG-CoA+3
Metabolic

Fermentation (Anaerobic)

Regeneration of NAD⁺ from NADH under anaerobic conditions.

PyruvateNADHNAD⁺+4
Metabolic

Glyoxylate Cycle

Net conversion of acetyl-CoA to oxaloacetate, bypassing CO₂ loss steps of TCA.

Acetyl-CoAIsocitrateGlyoxylate+3
Metabolic

Nitrogen Fixation

Reduction of atmospheric N₂ to ammonia by nitrogenase.

N₂NH₃ATP+3
Metabolic

CAM Photosynthesis

Temporal separation of CO₂ fixation (night) and Calvin cycle (day) to conserve water.

CO₂PEPOxaloacetate+3
Metabolic

C4 Photosynthesis

Spatial separation of initial CO₂ fixation and Calvin cycle to concentrate CO₂.

CO₂PEPOxaloacetate+3