Home/Isocitrate lyase

Enzyme

1 pathway

Isocitrate lyase

Found in 1 curated pathway across 1 category.

Interaction Network

Loading graph…

Active In Categories

Frequently Co-occurring Molecules

Acetyl-CoA×1 Isocitrate×1 Glyoxylate×1 Succinate×1 Malate×1 Oxaloacetate×1

Frequently Co-occurring Enzymes

Malate synthase×1 Citrate synthase×1 Aconitase×1 Malate dehydrogenase×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Glyoxylate Cycle

Net conversion of acetyl-CoA to oxaloacetate, bypassing CO₂ loss steps of TCA.

Acetyl-CoAIsocitrateGlyoxylate+3

Cross-Referenced

3

— connected via related pathways

Citric Acid Cycle (Krebs Cycle)

Oxidizes acetyl-CoA to CO₂, generating GTP, NADH, and FADH₂.

Acetyl-CoACitrateIsocitrate+6

β-Oxidation of Fatty Acids

Sequential removal of 2-carbon units from fatty acids as acetyl-CoA.

Fatty acyl-CoAAcetyl-CoACarnitine+5

Gluconeogenesis

Synthesis of glucose from non-carbohydrate precursors.

PyruvateOxaloacetatePhosphoenolpyruvate+4