Home/Oxaloacetate
Molecule
6 pathways

Oxaloacetate

Found in 6 curated pathways across 1 category.

Interaction Network

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Active In Categories

metabolic

Frequently Co-occurring Molecules

Malate×4Pyruvate×4Acetyl-CoA×3Isocitrate×2α-Ketoglutarate×2Succinate×2CO₂×2PEP×2Citrate×1Succinyl-CoA×1Fumarate×1Phosphoenolpyruvate×1

Frequently Co-occurring Enzymes

Malate dehydrogenase×3Citrate synthase×2PEP carboxylase×2NADP-malic enzyme×2RuBisCO×2Isocitrate dehydrogenase×1α-Ketoglutarate dehydrogenase×1Succinate dehydrogenase×1Pyruvate carboxylase×1PEP carboxykinase (PEPCK)×1Fructose-1,6-bisphosphatase×1Glucose-6-phosphatase×1

Cross-Referenced Pathways

6 direct · 6 cross-referenced · 12 shown

Direct Involvement

6
⚡
Metabolic

Citric Acid Cycle (Krebs Cycle)

Oxidizes acetyl-CoA to CO₂, generating GTP, NADH, and FADH₂.

Acetyl-CoACitrateIsocitrate+6
⚡
Metabolic

Gluconeogenesis

Synthesis of glucose from non-carbohydrate precursors.

PyruvateOxaloacetatePhosphoenolpyruvate+4
⚡
Metabolic

Amino Acid Catabolism

Degradation of amino acids to metabolic intermediates and ammonia.

Amino acidsα-KetoglutarateGlutamate+4
⚡
Metabolic

Glyoxylate Cycle

Net conversion of acetyl-CoA to oxaloacetate, bypassing CO₂ loss steps of TCA.

Acetyl-CoAIsocitrateGlyoxylate+3
⚡
Metabolic

CAM Photosynthesis

Temporal separation of CO₂ fixation (night) and Calvin cycle (day) to conserve water.

CO₂PEPOxaloacetate+3
⚡
Metabolic

C4 Photosynthesis

Spatial separation of initial CO₂ fixation and Calvin cycle to concentrate CO₂.

CO₂PEPOxaloacetate+3

Cross-Referenced

6
— connected via related pathways
⚡
Metabolic

Glycolysis

The breakdown of glucose into pyruvate, yielding ATP and NADH.

GlucoseGlucose-6-phosphateFructose-1,6-bisphosphate+4
⚡
Metabolic

Oxidative Phosphorylation

Electron transport chain coupled to ATP synthesis via chemiosmosis.

NADHFADH₂O₂+4
⚡
Metabolic

β-Oxidation of Fatty Acids

Sequential removal of 2-carbon units from fatty acids as acetyl-CoA.

Fatty acyl-CoAAcetyl-CoACarnitine+5
⚡
Metabolic

Photosynthesis – Light Reactions

Capture of light energy to produce ATP and NADPH, with O₂ as a byproduct.

Chlorophyll a/bH₂OO₂+5
⚡
Metabolic

Calvin Cycle (Light-Independent Reactions)

Fixes CO₂ into organic molecules using ATP and NADPH from light reactions.

CO₂Ribulose-1,5-bisphosphate (RuBP)3-Phosphoglycerate (3-PGA)+3
⚡
Metabolic

Urea Cycle

Converts toxic ammonia to urea for excretion.

NH₃ (ammonia)CO₂Carbamoyl phosphate+6