Home/dNTPs

Molecule

2 pathways

dNTPs

Found in 2 curated pathways across 2 categories.

Interaction Network

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Active In Categories

metabolic genetic

Frequently Co-occurring Molecules

PRPP×1 IMP×1 AMP×1 GMP×1 UMP×1 Orotate×1 Ribose-5-phosphate×1 THF (tetrahydrofolate)×1 dsDNA template×1 RNA primers×1 Okazaki fragments×1 PCNA×1

Frequently Co-occurring Enzymes

PRPP synthetase×1 Amidophosphoribosyltransferase×1 HGPRT×1 Dihydroorotate dehydrogenase×1 Ribonucleotide reductase×1 Thymidylate synthase×1 DNA Polymerase III/ε×1 Helicase (MCM complex)×1 Primase×1 DNA Ligase×1 Topoisomerase×1 Telomerase×1

Cross-Referenced Pathways

2 direct · 4 cross-referenced · 6 shown

Direct Involvement

2

Nucleotide Biosynthesis

De novo and salvage pathways for purine and pyrimidine nucleotide production.

Genetic Information

DNA Replication

Semi-conservative duplication of the genome before cell division.

dsDNA templatedNTPsRNA primers+3

Cross-Referenced

4

— connected via related pathways

Pentose Phosphate Pathway

Generates NADPH and ribose-5-phosphate for biosynthesis.

Glucose-6-phosphate6-PhosphogluconateRibulose-5-phosphate+3

Folate / One-Carbon Metabolism

Transfer of one-carbon units for nucleotide synthesis, methylation, and amino acid metabolism.

Tetrahydrofolate (THF)5-Methyl-THF5,10-Methylene-THF+6

Genetic Information

DNA Repair Pathways

Multiple mechanisms to detect and correct DNA damage.

Damaged DNAPCNARPA+4

Cell Cycle Checkpoints

Surveillance mechanisms ensuring genomic integrity at each cell cycle phase.