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Genetic Information Pathways
DNA replication, repair, transcription, and RNA processing
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Genetic Information
DNA Replication
Semi-conservative duplication of the genome before cell division.
dsDNA templatedNTPsRNA primers+3
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Genetic Information
Transcription
Synthesis of RNA from a DNA template by RNA polymerase.
DNA templatemRNANTPs+4
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Genetic Information
Translation (Protein Synthesis)
Ribosome-mediated synthesis of polypeptides from mRNA templates.
mRNAtRNAAmino acids+4
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Genetic Information
DNA Repair Pathways
Multiple mechanisms to detect and correct DNA damage.
Damaged DNAPCNARPA+4
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Genetic Information
Epigenetic Regulation
Heritable changes in gene expression without altering the DNA sequence.
5-MethylcytosineHistone H3/H4CpG islands+4
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Genetic Information
RNA Processing & Splicing
Post-transcriptional modifications converting pre-mRNA to mature mRNA.
Pre-mRNAsnRNPs (U1-U6)Exons+6
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Genetic Information
RNA Interference (RNAi)
Post-transcriptional gene silencing by small interfering RNAs.
dsRNAsiRNAmiRNA+5
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Genetic Information
Protein Folding & Quality Control
Chaperone-assisted folding and ER quality control of newly synthesized proteins.
Hsp70 (BiP/GRP78)Hsp90Chaperonin (TriC/CCT)+4