Home/THF (tetrahydrofolate)

Molecule

1 pathway

THF (tetrahydrofolate)

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

PRPP×1 IMP×1 AMP×1 GMP×1 UMP×1 Orotate×1 Ribose-5-phosphate×1 dNTPs×1

Frequently Co-occurring Enzymes

PRPP synthetase×1 Amidophosphoribosyltransferase×1 HGPRT×1 Dihydroorotate dehydrogenase×1 Ribonucleotide reductase×1 Thymidylate synthase×1

Cross-Referenced Pathways

1 direct · 2 cross-referenced · 3 shown

Direct Involvement

1

Nucleotide Biosynthesis

De novo and salvage pathways for purine and pyrimidine nucleotide production.

Cross-Referenced

2

— connected via related pathways

Pentose Phosphate Pathway

Generates NADPH and ribose-5-phosphate for biosynthesis.

Glucose-6-phosphate6-PhosphogluconateRibulose-5-phosphate+3

Folate / One-Carbon Metabolism

Transfer of one-carbon units for nucleotide synthesis, methylation, and amino acid metabolism.

Tetrahydrofolate (THF)5-Methyl-THF5,10-Methylene-THF+6