Home/RPA

Molecule

2 pathways

RPA

Found in 2 curated pathways across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

PCNA×2 dsDNA template×1 dNTPs×1 RNA primers×1 Okazaki fragments×1 Damaged DNA×1 RAD51×1 Ku70/Ku80×1 BRCA1/BRCA2×1 γH2AX×1

Frequently Co-occurring Enzymes

DNA Polymerase III/ε×1 Helicase (MCM complex)×1 Primase×1 DNA Ligase×1 Topoisomerase×1 Telomerase×1 DNA glycosylases (BER)×1 XPC/XPA (NER)×1 MSH2/MLH1 (MMR)×1 RAD51 (HR)×1 DNA-PKcs (NHEJ)×1 PARP1×1

Cross-Referenced Pathways

2 direct · 1 cross-referenced · 3 shown

Direct Involvement

2

Genetic Information

DNA Replication

Semi-conservative duplication of the genome before cell division.

dsDNA templatedNTPsRNA primers+3

Genetic Information

DNA Repair Pathways

Multiple mechanisms to detect and correct DNA damage.

Damaged DNAPCNARPA+4

Cross-Referenced

1

— connected via related pathways

Cell Cycle Checkpoints

Surveillance mechanisms ensuring genomic integrity at each cell cycle phase.