Enzyme
2 pathways
JAK1
Found in 2 curated pathways across 2 categories.
Interaction Network
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Active In Categories
Frequently Co-occurring Molecules
Frequently Co-occurring Enzymes
Cross-Referenced Pathways
2 direct · 3 cross-referenced · 5 shown
Direct Involvement
2
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Signal Transduction
JAK-STAT Pathway
Cytokine-driven signaling from receptor to gene expression via STAT dimerization.
Cytokines (IL-6, IFN, EPO)JAK1/2/3, TYK2STAT1-6+2
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Immune Response
Type I Interferon Response
Antiviral defense system activating hundreds of interferon-stimulated genes.
IFN-αIFN-βIFNAR1/2+7
Cross-Referenced
3
— connected via related pathways