BioPath / KB
Pathways for Medicine
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Modules · Core
01Why Pathways Matter02Reading Pathway Diagrams03Glycolysis & the TCA Cycle04Oxidative Phosphorylation05Lipid & Amino Acid Metabolism06Signal Transduction Basics07RTKs, RAS-MAPK & PI3K-AKT08Wnt, Hedgehog & Notch09Immune Signaling Pathways10Apoptosis & Cell Cycle Control11Disease Pathways & Drug Targets12Capstone: Cross-Pathway Reasoning
Evidence-first knowledge base. For education only — not medical advice. Verify against current guidelines.
Home/Chk1
Molecule & Enzyme
2 pathways

Chk1

Found in 2 curated pathways across 1 category.

Interaction Network

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Active In Categories

cell-cycle

Frequently Co-occurring Molecules

p53×2p21×2ATM×2ATR×2Chk2×2γH2AX×2Mad2×2BubR1×214-3-3σ×2

Frequently Co-occurring Enzymes

ATM kinase×2ATR kinase×2Chk2×2Wee1×2Cdc25 phosphatases×2

Cross-Referenced Pathways

2 direct · 3 cross-referenced · 5 shown

Direct Involvement

2
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Cell Cycle

Cell Cycle Checkpoints

Surveillance mechanisms ensuring genomic integrity at each cell cycle phase.

p53p21ATM+7
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Cell Cycle

Cell Cycle Checkpoints

Surveillance mechanisms ensuring genomic integrity at each cell cycle phase.

p53p21ATM+7

Cross-Referenced

3
— connected via related pathways
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Genetic Information

DNA Repair Pathways

Multiple mechanisms to detect and correct DNA damage.

Damaged DNAPCNARPA+4
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Cell Cycle

Cell Cycle Regulation

Ordered progression through G1, S, G2, and M phases via cyclin-CDK complexes.

Cyclin D/E/A/BCDK1/2/4/6Rb+5
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Cell Death

Intrinsic Apoptosis (Mitochondrial)

Cell death triggered by internal stress via mitochondrial cytochrome c release.

BAXBAKBCL-2+7
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