🔄
Cell Cycle Pathways
Cell division, growth, and checkpoints
🔄
Cell Cycle
Cell Cycle Regulation
Ordered progression through G1, S, G2, and M phases via cyclin-CDK complexes.
Cyclin D/E/A/BCDK1/2/4/6Rb+5
🔄
Cell Cycle
Mitosis
Nuclear division producing two genetically identical daughter nuclei.
CondensinCohesinKinetochore proteins+3
🔄
Cell Cycle
Meiosis
Two successive divisions producing four haploid gametes with genetic diversity.
Synaptonemal complexCohesin (Rec8)Spo11+3
🔄
Cell Cycle
Cell Cycle Checkpoints
Surveillance mechanisms ensuring genomic integrity at each cell cycle phase.
p53p21ATM+7
🔄
Cell Cycle
Cellular Senescence
Permanent cell cycle arrest in response to stress or telomere shortening.
p53p21p16INK4a+4
🔄
Cell Cycle
Cytokinesis
Physical division of the cytoplasm following nuclear division.
ActinMyosin IIRhoA+4