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Cell Cycle
Eukaryotes
Mitosis
Nuclear division producing two genetically identical daughter nuclei.
Overview
Mitosis consists of five stages: prophase, prometaphase, metaphase, anaphase, and telophase. Cytokinesis typically follows to divide the cytoplasm. The spindle assembly checkpoint ensures all chromosomes are properly attached before anaphase.
Cellular Location
Nucleus → whole cell
Clinical Significance
Essential for growth and tissue repair; target of anti-mitotic chemotherapies (taxanes, vinca alkaloids); errors cause aneuploidy.