Home/Lyn

Molecule

1 pathway

Lyn

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

BCR (membrane Ig)×1 Igα/Igβ (CD79a/b)×1 Syk×1 BTK×1 PLCγ2×1 BLNK×1 DAG×1 IP3×1 NFAT×1 NF-κB×1

Frequently Co-occurring Enzymes

Lyn kinase×1 Syk kinase×1 BTK×1 PLCγ2×1 PI3Kδ×1 PKCβ×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Immune Response

B Cell Receptor Signaling

Antigen-specific activation of B lymphocytes for antibody production.

BCR (membrane Ig)Igα/Igβ (CD79a/b)Lyn+8

Cross-Referenced

3

— connected via related pathways

Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6

Signal Transduction

NF-κB Pathway

Master regulator of inflammation, immunity, and cell survival.

NF-κB (p65/RelA, p50)IκBαIKKα/β/γ+4

Immune Response

T Cell Receptor Signaling

Antigen-specific activation of T lymphocytes via TCR-MHC interaction.

TCR-CD3 complexMHC-peptideCD4/CD8+7