Home/Dishevelled

Molecule

2 pathways

Dishevelled

Found in 2 curated pathways across 2 categories.

Interaction Network

Loading graph…

Active In Categories

signaling developmental

Frequently Co-occurring Molecules

Wnt ligands×1 Frizzled receptor×1 LRP5/6×1 β-Catenin×1 APC×1 Axin×1 TCF/LEF×1 Wnt5a/Wnt11×1 Frizzled×1 Vangl1/2×1 Prickle×1 Celsr1-3×1

Frequently Co-occurring Enzymes

GSK-3β×1 CK1α×1 Porcupine×1 Tankyrase×1 RhoA GTPase×1 Rac1 GTPase×1 ROCK kinase×1 JNK kinase×1 DAAM1 (formin)×1

Cross-Referenced Pathways

2 direct · 2 cross-referenced · 4 shown

Direct Involvement

2

Signal Transduction

Wnt/β-Catenin Pathway

Controls cell fate, proliferation, and polarity through β-catenin stabilization.

Wnt ligandsFrizzled receptorLRP5/6+5

Planar Cell Polarity (PCP)

Non-canonical Wnt pathway coordinating tissue-level cell orientation.

Wnt5a/Wnt11FrizzledVangl1/2+6

Cross-Referenced

2

— connected via related pathways

Signal Transduction

Notch Signaling Pathway

Juxtacrine signaling controlling cell fate decisions via proteolytic receptor activation.

Notch 1-4 receptorsDelta-like ligands (DLL1, DLL3, DLL4)Jagged ligands (JAG1, JAG2)+3

Hedgehog Signaling Pathway

Morphogen gradient pathway controlling tissue patterning and stem cell maintenance.