Home/Prickle

Molecule

1 pathway

Prickle

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

Wnt5a/Wnt11×1 Frizzled×1 Vangl1/2×1 Celsr1-3×1 Dishevelled×1 RhoA×1 Rac1×1 JNK×1

Frequently Co-occurring Enzymes

RhoA GTPase×1 Rac1 GTPase×1 ROCK kinase×1 JNK kinase×1 DAAM1 (formin)×1

Cross-Referenced Pathways

1 direct · 2 cross-referenced · 3 shown

Direct Involvement

1

Planar Cell Polarity (PCP)

Non-canonical Wnt pathway coordinating tissue-level cell orientation.

Wnt5a/Wnt11FrizzledVangl1/2+6

Cross-Referenced

2

— connected via related pathways

Signal Transduction

Wnt/β-Catenin Pathway

Controls cell fate, proliferation, and polarity through β-catenin stabilization.

Wnt ligandsFrizzled receptorLRP5/6+5

Hedgehog Signaling Pathway

Morphogen gradient pathway controlling tissue patterning and stem cell maintenance.