Home/CDK1/2/4/6

Molecule

1 pathway

CDK1/2/4/6

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

Cyclin D/E/A/B×1 Rb×1 E2F×1 p53×1 p21×1 p27×1 p16INK4a×1

Frequently Co-occurring Enzymes

CDK4/6×1 CDK2×1 CDK1×1 APC/C (ubiquitin ligase)×1 SCF (ubiquitin ligase)×1 ATM/ATR kinases×1

Cross-Referenced Pathways

1 direct · 2 cross-referenced · 3 shown

Direct Involvement

1

Cell Cycle Regulation

Ordered progression through G1, S, G2, and M phases via cyclin-CDK complexes.

Cyclin D/E/A/BCDK1/2/4/6Rb+5

Cross-Referenced

2

— connected via related pathways

Genetic Information

DNA Replication

Semi-conservative duplication of the genome before cell division.

dsDNA templatedNTPsRNA primers+3

Intrinsic Apoptosis (Mitochondrial)

Cell death triggered by internal stress via mitochondrial cytochrome c release.