Home/Src kinase

Enzyme

2 pathways

Src kinase

Found in 2 curated pathways across 2 categories.

Interaction Network

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Active In Categories

signaling muscle

Frequently Co-occurring Molecules

VEGF-A/B/C/D×1 VEGFR-1/2/3×1 Neuropilin×1 Angiopoietin-1/2×1 Tie2×1 HIF-1α×1 Integrins (αβ dimers)×1 Fibronectin×1 Collagen×1 Laminin×1 Talin×1 Kindlin×1

Frequently Co-occurring Enzymes

VEGFR-2 kinase×1 PLCγ×1 PI3K×1 eNOS×1 FAK (focal adhesion kinase)×1 ILK (integrin-linked kinase)×1 MLCK×1

Cross-Referenced Pathways

2 direct · 4 cross-referenced · 6 shown

Direct Involvement

2

Signal Transduction

VEGF Signaling (Angiogenesis)

Vascular endothelial growth factor driving new blood vessel formation.

VEGF-A/B/C/DVEGFR-1/2/3Neuropilin+3

Muscle & Cytoskeleton

Integrin Signaling & Focal Adhesions

Cell-ECM adhesion receptors transducing mechanical and chemical signals.

Integrins (αβ dimers)FibronectinCollagen+7

Cross-Referenced

4

— connected via related pathways

Signal Transduction

MAPK/ERK Pathway

RAS–RAF–MEK–ERK cascade transducing growth factor signals to the nucleus.

Growth factors (EGF, PDGF)RAS-GTPRAF+3

Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6

Signal Transduction

Notch Signaling Pathway

Juxtacrine signaling controlling cell fate decisions via proteolytic receptor activation.

Notch 1-4 receptorsDelta-like ligands (DLL1, DLL3, DLL4)Jagged ligands (JAG1, JAG2)+3

Muscle & Cytoskeleton

Actin Cytoskeleton Dynamics

Rho GTPase-regulated actin polymerization driving cell shape and motility.

G-actinF-actinArp2/3 complex+8