Home/ILK (integrin-linked kinase)

Enzyme

1 pathway

ILK (integrin-linked kinase)

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

Integrins (αβ dimers)×1 Fibronectin×1 Collagen×1 Laminin×1 Talin×1 Kindlin×1 Vinculin×1 Paxillin×1 FAK×1 Src×1

Frequently Co-occurring Enzymes

FAK (focal adhesion kinase)×1 Src kinase×1 MLCK×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Muscle & Cytoskeleton

Integrin Signaling & Focal Adhesions

Cell-ECM adhesion receptors transducing mechanical and chemical signals.

Integrins (αβ dimers)FibronectinCollagen+7

Cross-Referenced

3

— connected via related pathways

Signal Transduction

MAPK/ERK Pathway

RAS–RAF–MEK–ERK cascade transducing growth factor signals to the nucleus.

Growth factors (EGF, PDGF)RAS-GTPRAF+3

Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6

Muscle & Cytoskeleton

Actin Cytoskeleton Dynamics

Rho GTPase-regulated actin polymerization driving cell shape and motility.

G-actinF-actinArp2/3 complex+8