Home/PDK1

Molecule & Enzyme

2 pathways

PDK1

Found in 2 curated pathways across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

PIP2×2 PIP3×2 AKT/PKB×2 mTORC1×2 mTORC2×2 PTEN×2 4E-BP1×2 S6K1×2

Frequently Co-occurring Enzymes

PI3K×2 AKT×2 mTOR×2 PTEN×2 S6 kinase×2

Cross-Referenced Pathways

2 direct · 2 cross-referenced · 4 shown

Direct Involvement

2

Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6

Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6

Cross-Referenced

2

— connected via related pathways

Signal Transduction

MAPK/ERK Pathway

RAS–RAF–MEK–ERK cascade transducing growth factor signals to the nucleus.

Growth factors (EGF, PDGF)RAS-GTPRAF+3

Signal Transduction

Insulin Signaling Pathway

Insulin receptor activation driving glucose uptake and anabolic metabolism.

InsulinInsulin receptorIRS-1/2+6