Home/AKT/PKB

Molecule

1 pathway

AKT/PKB

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

PIP2×1 PIP3×1 mTORC1×1 mTORC2×1 PTEN×1 PDK1×1 4E-BP1×1 S6K1×1

Frequently Co-occurring Enzymes

PI3K×1 AKT×1 mTOR×1 PTEN×1 PDK1×1 S6 kinase×1

Cross-Referenced Pathways

1 direct · 2 cross-referenced · 3 shown

Direct Involvement

1

Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6

Cross-Referenced

2

— connected via related pathways

Signal Transduction

MAPK/ERK Pathway

RAS–RAF–MEK–ERK cascade transducing growth factor signals to the nucleus.

Growth factors (EGF, PDGF)RAS-GTPRAF+3

Signal Transduction

Insulin Signaling Pathway

Insulin receptor activation driving glucose uptake and anabolic metabolism.

InsulinInsulin receptorIRS-1/2+6