Home/mGluR1-8

Molecule

1 pathway

mGluR1-8

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

Glutamate×1 AMPA receptors×1 NMDA receptors×1 Kainate receptors×1 Glutamine×1 EAAT1/2 (astrocyte transporters)×1 Mg²⁺×1 Ca²⁺×1

Frequently Co-occurring Enzymes

Glutaminase×1 Glutamine synthetase (astrocytes)×1 CaMKII×1 Calcineurin×1 PKC×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Glutamate Signaling

Excitatory neurotransmission via ionotropic and metabotropic glutamate receptors.

GlutamateAMPA receptorsNMDA receptors+6

Cross-Referenced

3

— connected via related pathways

Signal Transduction

Calcium Signaling

Ca²⁺ as a universal second messenger controlling diverse cellular processes.

Ca²⁺CalmodulinIP3+4

Synaptic Transmission

Chemical neurotransmission across synaptic clefts between neurons.

GlutamateGABAAcetylcholine+6

Long-Term Potentiation / Depression (LTP/LTD)

Activity-dependent strengthening or weakening of synaptic connections.

NMDA receptorAMPA receptorCa²⁺+6