Home/MDR1/P-gp (ABCB1)

Enzyme

1 pathway

MDR1/P-gp (ABCB1)

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

ATP×1 Lipids×1 Drugs×1 Bile salts×1 Chloride ions×1 Cholesterol×1 Peptides×1

Frequently Co-occurring Enzymes

MRP1 (ABCC1)×1 BCRP (ABCG2)×1 CFTR (ABCC7)×1 ABCA1×1 TAP1/TAP2×1

Cross-Referenced Pathways

1 direct · 2 cross-referenced · 3 shown

Direct Involvement

1

Membrane Transport

ABC Transporter Superfamily

ATP-driven efflux pumps transporting diverse substrates across membranes.

ATPLipidsDrugs+4

Cross-Referenced

2

— connected via related pathways

Membrane Transport

Receptor-Mediated Endocytosis

Clathrin-coated pit internalization of receptor-ligand complexes.

ClathrinAP-2Dynamin+5

Membrane Transport

Ion Channel Signaling

Selective ion flux through membrane channels driving electrical and chemical signals.

Na⁺K⁺Ca²⁺+5