Home/Phosphofructokinase-1 (PFK-1)

Enzyme

1 pathway

Phosphofructokinase-1 (PFK-1)

Found in 1 curated pathway across 1 category.

Interaction Network

Loading graph…

Active In Categories

Frequently Co-occurring Molecules

Glucose×1 Glucose-6-phosphate×1 Fructose-1,6-bisphosphate×1 Glyceraldehyde-3-phosphate×1 Pyruvate×1 ATP×1 NADH×1

Frequently Co-occurring Enzymes

Hexokinase×1 Pyruvate kinase×1 Aldolase×1 Enolase×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Glycolysis

The breakdown of glucose into pyruvate, yielding ATP and NADH.

GlucoseGlucose-6-phosphateFructose-1,6-bisphosphate+4

Cross-Referenced

3

— connected via related pathways

Citric Acid Cycle (Krebs Cycle)

Oxidizes acetyl-CoA to CO₂, generating GTP, NADH, and FADH₂.

Acetyl-CoACitrateIsocitrate+6

Pentose Phosphate Pathway

Generates NADPH and ribose-5-phosphate for biosynthesis.

Glucose-6-phosphate6-PhosphogluconateRibulose-5-phosphate+3

Gluconeogenesis

Synthesis of glucose from non-carbohydrate precursors.

PyruvateOxaloacetatePhosphoenolpyruvate+4