Home/NKp30/46

Molecule

1 pathway

NKp30/46

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

NKG2D×1 CD16 (FcγRIII)×1 KIR×1 NKG2A/CD94×1 Perforin×1 Granzyme B×1 IFN-γ×1 MICA/MICB×1

Frequently Co-occurring Enzymes

Granzyme B (serine protease)×1 Perforin (pore-forming)×1 Vav1×1 PI3K×1 PLCγ2×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Immune Response

Natural Killer Cell Activation

Innate lymphocyte killing of virus-infected and tumor cells via receptor balance.

NKG2DNKp30/46CD16 (FcγRIII)+6

Cross-Referenced

3

— connected via related pathways

Immune Response

Type I Interferon Response

Antiviral defense system activating hundreds of interferon-stimulated genes.

IFN-αIFN-βIFNAR1/2+7

Immune Response

Antigen Processing & Presentation

MHC-mediated display of peptide antigens to T cells.

MHC class IMHC class IIβ2-microglobulin+6

Intrinsic Apoptosis (Mitochondrial)

Cell death triggered by internal stress via mitochondrial cytochrome c release.