Home/RALDH2

Enzyme

1 pathway

RALDH2

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

Hes7/Her1 (oscillators)×1 LFNG (Notch modifier)×1 Axin2 (Wnt target)×1 FGF8×1 Retinoic acid×1 MESP2×1 Tbx6×1

Frequently Co-occurring Enzymes

Notch (NICD)×1 GSK-3β×1 FGFR kinase×1

Cross-Referenced Pathways

1 direct · 4 cross-referenced · 5 shown

Direct Involvement

1

Somitogenesis (Segmentation Clock)

Oscillating gene expression driving periodic formation of somites.

Hes7/Her1 (oscillators)LFNG (Notch modifier)Axin2 (Wnt target)+4

Cross-Referenced

4

— connected via related pathways

Signal Transduction

Wnt/β-Catenin Pathway

Controls cell fate, proliferation, and polarity through β-catenin stabilization.

Wnt ligandsFrizzled receptorLRP5/6+5

Signal Transduction

Notch Signaling Pathway

Juxtacrine signaling controlling cell fate decisions via proteolytic receptor activation.

Notch 1-4 receptorsDelta-like ligands (DLL1, DLL3, DLL4)Jagged ligands (JAG1, JAG2)+3

Retinoic Acid Signaling

Vitamin A-derived morphogen controlling anterior-posterior patterning.

RetinolRetinaldehydeATRA+4

FGF Signaling

Fibroblast growth factor signaling controlling proliferation, differentiation, and organogenesis.

FGF1-22FGFR1-4FRS2+3