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Molecule

1 pathway

NLS

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

Importin α/β×1 Exportin 1 (CRM1)×1 RanGTP/GDP×1 RCC1 (RanGEF)×1 RanGAP1×1 Nucleoporins (Nups)×1 NES×1

Frequently Co-occurring Enzymes

RanGTPase×1 RCC1 (guanine nucleotide exchange factor)×1 RanGAP1 (GTPase activating protein)×1

Cross-Referenced Pathways

1 direct · 2 cross-referenced · 3 shown

Direct Involvement

1

Membrane Transport

Nuclear Import/Export

Ran-GTPase-driven transport of macromolecules through nuclear pore complexes.

Importin α/βExportin 1 (CRM1)RanGTP/GDP+5

Cross-Referenced

2

— connected via related pathways

Genetic Information

RNA Processing & Splicing

Post-transcriptional modifications converting pre-mRNA to mature mRNA.

Pre-mRNAsnRNPs (U1-U6)Exons+6

Cell Cycle Regulation

Ordered progression through G1, S, G2, and M phases via cyclin-CDK complexes.

Cyclin D/E/A/BCDK1/2/4/6Rb+5