Home/miR-200 family

Molecule

1 pathway

miR-200 family

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

E-cadherin×1 N-cadherin×1 Vimentin×1 Fibronectin×1 Snail/Slug×1 Twist1/2×1 ZEB1/2×1

Frequently Co-occurring Enzymes

GSK-3β (Snail phosphorylation)×1 LOX (E-cadherin repression)×1 MMPs (matrix degradation)×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Epithelial-Mesenchymal Transition (EMT)

Cellular program converting epithelial cells to motile mesenchymal phenotype.

E-cadherinN-cadherinVimentin+5

Cross-Referenced

3

— connected via related pathways

Signal Transduction

Wnt/β-Catenin Pathway

Controls cell fate, proliferation, and polarity through β-catenin stabilization.

Wnt ligandsFrizzled receptorLRP5/6+5

Signal Transduction

Notch Signaling Pathway

Juxtacrine signaling controlling cell fate decisions via proteolytic receptor activation.

Notch 1-4 receptorsDelta-like ligands (DLL1, DLL3, DLL4)Jagged ligands (JAG1, JAG2)+3

TGF-β/BMP Signaling

Multifunctional cytokine signaling controlling growth, differentiation, and immune regulation.

TGF-β1/2/3BMP2/4/7Activin+5