Home/Hsp70 (BiP/GRP78)

Molecule

1 pathway

Hsp70 (BiP/GRP78)

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

Hsp90×1 Chaperonin (TriC/CCT)×1 Calnexin×1 Calreticulin×1 Ubiquitin×1 Proteasome×1

Frequently Co-occurring Enzymes

Hsp70 ATPase×1 PDI (protein disulfide isomerase)×1 Glucosidases I/II×1 UGGT×1 E1/E2/E3 ubiquitin ligases×1

Cross-Referenced Pathways

1 direct · 2 cross-referenced · 3 shown

Direct Involvement

1

Genetic Information

Protein Folding & Quality Control

Chaperone-assisted folding and ER quality control of newly synthesized proteins.

Hsp70 (BiP/GRP78)Hsp90Chaperonin (TriC/CCT)+4

Cross-Referenced

2

— connected via related pathways

Genetic Information

Translation (Protein Synthesis)

Ribosome-mediated synthesis of polypeptides from mRNA templates.

mRNAtRNAAmino acids+4

Autophagy

Self-digestion pathway recycling cellular components via lysosomal degradation.

ULK1 complexBeclin-1VPS34+6