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01Why Pathways Matter02Reading Pathway Diagrams03Glycolysis & the TCA Cycle04Oxidative Phosphorylation05Lipid & Amino Acid Metabolism06Signal Transduction Basics07RTKs, RAS-MAPK & PI3K-AKT08Wnt, Hedgehog & Notch09Immune Signaling Pathways10Apoptosis & Cell Cycle Control11Disease Pathways & Drug Targets12Capstone: Cross-Pathway Reasoning
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Home/GRB2-SOS
Enzyme
1 pathway

GRB2-SOS

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

developmental

Frequently Co-occurring Molecules

FGF1-22×1FGFR1-4×1FRS2×1Heparan sulfate×1Klotho (FGF23 co-receptor)×1Sprouty (negative regulator)×1

Frequently Co-occurring Enzymes

FGFR kinase×1FRS2 adaptor×1PLCγ×1PI3K×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1
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Developmental

FGF Signaling

Fibroblast growth factor signaling controlling proliferation, differentiation, and organogenesis.

FGF1-22FGFR1-4FRS2+3

Cross-Referenced

3
— connected via related pathways
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Signal Transduction

MAPK/ERK Pathway

RAS–RAF–MEK–ERK cascade transducing growth factor signals to the nucleus.

Growth factors (EGF, PDGF)RAS-GTPRAF+3
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Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6
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Developmental

Hedgehog Signaling Pathway

Morphogen gradient pathway controlling tissue patterning and stem cell maintenance.

SHHIHHDHH+4
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