Home/GLI1/2/3

Molecule

1 pathway

GLI1/2/3

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

SHH×1 IHH×1 DHH×1 PTCH1×1 SMO×1 SUFU×1

Frequently Co-occurring Enzymes

SMO (GPCR-like)×1 PKA×1 GSK-3β×1 CK1×1 HHAT×1

Cross-Referenced Pathways

1 direct · 2 cross-referenced · 3 shown

Direct Involvement

1

Hedgehog Signaling Pathway

Morphogen gradient pathway controlling tissue patterning and stem cell maintenance.

Cross-Referenced

2

— connected via related pathways

Signal Transduction

Wnt/β-Catenin Pathway

Controls cell fate, proliferation, and polarity through β-catenin stabilization.

Wnt ligandsFrizzled receptorLRP5/6+5

Signal Transduction

Notch Signaling Pathway

Juxtacrine signaling controlling cell fate decisions via proteolytic receptor activation.

Notch 1-4 receptorsDelta-like ligands (DLL1, DLL3, DLL4)Jagged ligands (JAG1, JAG2)+3