Home/G-actin

Molecule

1 pathway

G-actin

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

F-actin×1 Arp2/3 complex×1 Formins (mDia)×1 Cofilin×1 Profilin×1 Rac1×1 Cdc42×1 RhoA×1 N-WASP×1 WAVE×1

Frequently Co-occurring Enzymes

Arp2/3 complex×1 Formins×1 ROCK kinase×1 LIMK (phosphorylates cofilin)×1 PAK kinase×1 Myosin II×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Muscle & Cytoskeleton

Actin Cytoskeleton Dynamics

Rho GTPase-regulated actin polymerization driving cell shape and motility.

G-actinF-actinArp2/3 complex+8

Cross-Referenced

3

— connected via related pathways

Signal Transduction

PI3K/AKT/mTOR Pathway

Regulates cell survival, growth, and metabolism via phosphoinositide signaling.

PIP2PIP3AKT/PKB+6

Signal Transduction

G Protein-Coupled Receptor (GPCR) Signaling

Seven-transmembrane receptors activating heterotrimeric G proteins.

GPCRsGαs/Gαi/Gαq/Gα12Gβγ+6

Epithelial-Mesenchymal Transition (EMT)

Cellular program converting epithelial cells to motile mesenchymal phenotype.

E-cadherinN-cadherinVimentin+5