Home/Clathrin

Molecule

2 pathways

Clathrin

Found in 2 curated pathways across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

AP-2×1 Dynamin×1 Rab5×1 Rab7×1 EEA1×1 ESCRT complex×1 LDL/LDLR×1 COPII coat×1 COPI coat×1 SNARE proteins×1 Rab GTPases×1 Sec61 translocon×1

Frequently Co-occurring Enzymes

Dynamin (GTPase)×1 PI3K (VPS34)×1 Rab GTPases×1 AAK1 kinase×1 Sar1 GTPase (COPII)×1 ARF1 GTPase (COPI)×1 NSF ATPase×1 Signal peptidase×1

Cross-Referenced Pathways

2 direct · 2 cross-referenced · 4 shown

Direct Involvement

2

Membrane Transport

Receptor-Mediated Endocytosis

Clathrin-coated pit internalization of receptor-ligand complexes.

ClathrinAP-2Dynamin+5

Membrane Transport

Vesicular Transport (Secretory Pathway)

ER-to-Golgi-to-plasma membrane trafficking via coated vesicles.

COPII coatCOPI coatClathrin+4

Cross-Referenced

2

— connected via related pathways

Genetic Information

Protein Folding & Quality Control

Chaperone-assisted folding and ER quality control of newly synthesized proteins.

Hsp70 (BiP/GRP78)Hsp90Chaperonin (TriC/CCT)+4

Autophagy

Self-digestion pathway recycling cellular components via lysosomal degradation.

ULK1 complexBeclin-1VPS34+6