Home/PCSK9

Enzyme

1 pathway

PCSK9

Found in 1 curated pathway across 1 category.

Interaction Network

Loading graph…

Active In Categories

Frequently Co-occurring Molecules

Chylomicrons×1 VLDL×1 IDL×1 LDL×1 HDL×1 ApoB-100×1 ApoB-48×1 ApoA-I×1 ApoE×1 ApoC-II×1 CETP×1

Frequently Co-occurring Enzymes

Lipoprotein lipase (LPL)×1 Hepatic lipase×1 LCAT×1 ACAT×1 MTP×1 LDLR×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Lipid Metabolism

Lipoprotein Metabolism

Transport of lipids in blood via chylomicrons, VLDL, LDL, and HDL particles.

ChylomicronsVLDLIDL+8

Cross-Referenced

3

— connected via related pathways

β-Oxidation of Fatty Acids

Sequential removal of 2-carbon units from fatty acids as acetyl-CoA.

Fatty acyl-CoAAcetyl-CoACarnitine+5

Membrane Transport

Receptor-Mediated Endocytosis

Clathrin-coated pit internalization of receptor-ligand complexes.

ClathrinAP-2Dynamin+5

Lipid Metabolism

Cholesterol Biosynthesis (Mevalonate Pathway)

Multi-step synthesis of cholesterol from acetyl-CoA via the mevalonate pathway.

Acetyl-CoAHMG-CoAMevalonate+8