Home/MyD88

Molecule

1 pathway

MyD88

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

TLR1-10×1 LPS×1 CpG DNA×1 dsRNA×1 TRIF×1 TRAM×1 TIRAP×1 Type I IFNs×1

Frequently Co-occurring Enzymes

IRAK1/4×1 TRAF6×1 TAK1×1 TBK1×1 IRF3/7×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

Immune Response

Toll-Like Receptor (TLR) Signaling

Pattern recognition receptors activating innate immune responses.

TLR1-10LPSCpG DNA+6

Cross-Referenced

3

— connected via related pathways

Signal Transduction

JAK-STAT Pathway

Cytokine-driven signaling from receptor to gene expression via STAT dimerization.

Cytokines (IL-6, IFN, EPO)JAK1/2/3, TYK2STAT1-6+2

Signal Transduction

NF-κB Pathway

Master regulator of inflammation, immunity, and cell survival.

NF-κB (p65/RelA, p50)IκBαIKKα/β/γ+4

Immune Response

Inflammasome Pathway

Intracellular sensor complexes activating inflammatory caspases and IL-1β/IL-18.

NLRP3ASCPro-caspase-1+6