Home/CYP11A1 (cholesterol side-chain cleavage)

Enzyme

1 pathway

CYP11A1 (cholesterol side-chain cleavage)

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

CRH×1 AVP×1 ACTH×1 Cortisol×1 Glucocorticoid receptor (GR)×1 Mineralocorticoid receptor (MR)×1 CBG (cortisol binding globulin)×1

Frequently Co-occurring Enzymes

CYP11B1 (11β-hydroxylase)×1 CYP17A1×1 CYP21A2×1 11β-HSD1/2×1

Cross-Referenced Pathways

1 direct · 3 cross-referenced · 4 shown

Direct Involvement

1

HPA Axis (Stress Response)

Hypothalamic-pituitary-adrenal axis regulating cortisol and stress response.

Cross-Referenced

3

— connected via related pathways

Signal Transduction

NF-κB Pathway

Master regulator of inflammation, immunity, and cell survival.

NF-κB (p65/RelA, p50)IκBαIKKα/β/γ+4

Signal Transduction

G Protein-Coupled Receptor (GPCR) Signaling

Seven-transmembrane receptors activating heterotrimeric G proteins.

GPCRsGαs/Gαi/Gαq/Gα12Gβγ+6

Signal Transduction

cAMP/PKA Signaling

Cyclic AMP as a second messenger activating protein kinase A.

cAMPATPPKA regulatory subunits+3