Home/ACE

Enzyme

1 pathway

ACE

Found in 1 curated pathway across 1 category.

Interaction Network

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Active In Categories

Frequently Co-occurring Molecules

Renin×1 Angiotensinogen×1 Angiotensin I×1 Angiotensin II×1 Ang(1-7)×1 Aldosterone×1 AT1 receptor×1 AT2 receptor×1 Mas receptor×1 ACE2×1

Frequently Co-occurring Enzymes

Renin (aspartyl protease)×1 ACE2×1 Aldosterone synthase (CYP11B2)×1

Cross-Referenced Pathways

1 direct · 2 cross-referenced · 3 shown

Direct Involvement

1

Renin-Angiotensin-Aldosterone System (RAAS)

Hormonal cascade regulating blood pressure, fluid balance, and electrolytes.

ReninAngiotensinogenAngiotensin I+7

Cross-Referenced

2

— connected via related pathways

Signal Transduction

G Protein-Coupled Receptor (GPCR) Signaling

Seven-transmembrane receptors activating heterotrimeric G proteins.

GPCRsGαs/Gαi/Gαq/Gα12Gβγ+6

Signal Transduction

Calcium Signaling

Ca²⁺ as a universal second messenger controlling diverse cellular processes.

Ca²⁺CalmodulinIP3+4